Registering for Central Alerting System (CAS) alerts

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The Medicines and Healthcare products Regulatory Agency (MHRA) Central Alerting System (CAS) is the national system for issuing patient safety alerts, important public health messages and other safety critical information to all providers, including GP practices.

Since 1 October 2019, the MHRA have sent CAS alerts directly to practices, replacing the established local patient safety CAS alert email cascade mechanisms. It will also be one of the main channels used to communicate information during any Brexit process.

If you have not already done so, it is important that you register to receive CAS alerts by using this portal (

Last updated : 22 Jan 2020